Abstract
The chemical structure and properties of tacrolimus, and the different properties among several analogues are introduced and compared. The current situation of its application is reviewed. The progress in fermentation of tacrolimus is presented and the existing problems are pointed out. The technology of metabolic engineering used in fermentation is introduced especially. Furthermore, its outlook in future is forecasted.
| Original language | English |
|---|---|
| Pages (from-to) | 34-37 |
| Number of pages | 4 |
| Journal | Xiandai Huagong/Modern Chemical Industry |
| Volume | 28 |
| Issue number | 2 |
| State | Published - Feb 2008 |
Keywords
- Metabolic engineering
- Streptomyces
- Tacrolimus