Pyrrolopyrrole aza-BODIPY near-infrared photosensitizer for dual-mode imaging-guided photothermal cancer therapy

Chaolong Wu; Xiaoyu Huang; Yunyun Tang; Wanyue Xiao; Liguo Sun; Jinjun Shao; Xiaochen Dong

doi:10.1039/C8CC07768A

Pyrrolopyrrole aza-BODIPY near-infrared photosensitizer for dual-mode imaging-guided photothermal cancer therapy

Chaolong Wu, Xiaoyu Huang, Yunyun Tang, Wanyue Xiao, Liguo Sun, Jinjun Shao, Xiaochen Dong

SCHOOL OF FLEXIBLE ELECTRONICS(FUTURE TECHNOLOGIES)|INSTITUTE OF ADVANCED MATERIALS(IAM)

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

A NIR photosensitizer pyrrolopyrrole aza-BODIPY (PPAB) was synthesized in a straightforward manner. Through the use of PPAB NPs as a photothermal agent, photoacoustic imaging (PAI) and NIR fluorescence imaging (NIR-FI) can be achieved in vivo. In addition, the photothermal ablation of tumor cells can be realized both in vitro and in vivo, even at a low concentration (0.5 mg kg⁻¹).

Original language	English
Pages (from-to)	790-793
Number of pages	4
Journal	Chemical Communications
Volume	55
Issue number	6
DOIs	https://doi.org/10.1039/C8CC07768A
State	Published - 2019

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title = "Pyrrolopyrrole aza-BODIPY near-infrared photosensitizer for dual-mode imaging-guided photothermal cancer therapy",

abstract = "A NIR photosensitizer pyrrolopyrrole aza-BODIPY (PPAB) was synthesized in a straightforward manner. Through the use of PPAB NPs as a photothermal agent, photoacoustic imaging (PAI) and NIR fluorescence imaging (NIR-FI) can be achieved in vivo. In addition, the photothermal ablation of tumor cells can be realized both in vitro and in vivo, even at a low concentration (0.5 mg kg−1).",

author = "Chaolong Wu and Xiaoyu Huang and Yunyun Tang and Wanyue Xiao and Liguo Sun and Jinjun Shao and Xiaochen Dong",

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year = "2019",

doi = "10.1039/C8CC07768A",

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T1 - Pyrrolopyrrole aza-BODIPY near-infrared photosensitizer for dual-mode imaging-guided photothermal cancer therapy

AU - Wu, Chaolong

AU - Huang, Xiaoyu

AU - Tang, Yunyun

AU - Xiao, Wanyue

AU - Sun, Liguo

AU - Shao, Jinjun

AU - Dong, Xiaochen

PY - 2019

Y1 - 2019

N2 - A NIR photosensitizer pyrrolopyrrole aza-BODIPY (PPAB) was synthesized in a straightforward manner. Through the use of PPAB NPs as a photothermal agent, photoacoustic imaging (PAI) and NIR fluorescence imaging (NIR-FI) can be achieved in vivo. In addition, the photothermal ablation of tumor cells can be realized both in vitro and in vivo, even at a low concentration (0.5 mg kg−1).

AB - A NIR photosensitizer pyrrolopyrrole aza-BODIPY (PPAB) was synthesized in a straightforward manner. Through the use of PPAB NPs as a photothermal agent, photoacoustic imaging (PAI) and NIR fluorescence imaging (NIR-FI) can be achieved in vivo. In addition, the photothermal ablation of tumor cells can be realized both in vitro and in vivo, even at a low concentration (0.5 mg kg−1).

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U2 - 10.1039/C8CC07768A

DO - 10.1039/C8CC07768A

M3 - 文章

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AN - SCOPUS:85059982876

SN - 1359-7345

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SP - 790

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JO - Chemical Communications

JF - Chemical Communications

IS - 6

ER -

Pyrrolopyrrole aza-BODIPY near-infrared photosensitizer for dual-mode imaging-guided photothermal cancer therapy

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