Ratiometric fluorescence assay for γ-glutamyltranspeptidase detection based on a single fluorophore via analyte-induced variation of substitution

Xianfeng Hou; Qingxiang Yu; Fang Zeng; Changmin Yu; Shuizhu Wu

doi:10.1039/c4cc00473f

Ratiometric fluorescence assay for γ-glutamyltranspeptidase detection based on a single fluorophore via analyte-induced variation of substitution

Xianfeng Hou, Qingxiang Yu, Fang Zeng, Changmin Yu, Shuizhu Wu

South China University of Technology

Research output: Contribution to journal › Article › peer-review

78 Scopus citations

Abstract

The first ratiometric fluorescent probe for γ-glutamyltranspeptidase (GGT) was developed, which functions through GGT-induced variation of substitution and subsequent changes in photophysical properties. It can detect GGT in human serum, and be used to visualize the endogenous GGT in ovarian cancer cells.

Original language	English
Pages (from-to)	3417-3420
Number of pages	4
Journal	Chemical Communications
Volume	50
Issue number	26
DOIs	https://doi.org/10.1039/c4cc00473f
State	Published - 4 Mar 2014
Externally published	Yes

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10.1039/c4cc00473f

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title = "Ratiometric fluorescence assay for γ-glutamyltranspeptidase detection based on a single fluorophore via analyte-induced variation of substitution",

abstract = "The first ratiometric fluorescent probe for γ-glutamyltranspeptidase (GGT) was developed, which functions through GGT-induced variation of substitution and subsequent changes in photophysical properties. It can detect GGT in human serum, and be used to visualize the endogenous GGT in ovarian cancer cells.",

author = "Xianfeng Hou and Qingxiang Yu and Fang Zeng and Changmin Yu and Shuizhu Wu",

year = "2014",

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AU - Hou, Xianfeng

AU - Yu, Qingxiang

AU - Zeng, Fang

AU - Yu, Changmin

AU - Wu, Shuizhu

PY - 2014/3/4

Y1 - 2014/3/4

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AB - The first ratiometric fluorescent probe for γ-glutamyltranspeptidase (GGT) was developed, which functions through GGT-induced variation of substitution and subsequent changes in photophysical properties. It can detect GGT in human serum, and be used to visualize the endogenous GGT in ovarian cancer cells.

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JO - Chemical Communications

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ER -

Ratiometric fluorescence assay for γ-glutamyltranspeptidase detection based on a single fluorophore via analyte-induced variation of substitution

Abstract

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