Recent advances in nanozymes for combating bacterial infection

Bacterial infection is a major threat to public health around the world. Currently, antibiotics remain the most extensive mode of medical treatment for bacterial infection. However, the overuse and misuse of antibiotics have exacerbated the emergence of antibiotic-resistant strains, especially during the COVID-19 pandemic. In addition, the improper and excessive use of biocides and disinfectants has a catastrophic impact on antibiotic management plans worldwide. Therefore, there is an urgent need for alternative antibacterial treatments to alleviate this crisis. In recent years, nanozymes have become promising new antibacterial agents because of their broad-spectrum antibacterial activity, less drug resistance, and high stability. This review focuses on the classification of nanozymes and research progress of nanozymes as antibacterial agents, as well as perspectives for future research in this field.