Recent advances in pH-responsive nanomaterials for anti-infective therapy

Xinyi Lv; Jiayao Zhang; Dongliang Yang; Jinjun Shao; Wenjun Wang; Qi Zhang; Xiaochen Dong

doi:10.1039/d0tb02177f

Recent advances in pH-responsive nanomaterials for anti-infective therapy

Xinyi Lv, Jiayao Zhang, Dongliang Yang, Jinjun Shao, Wenjun Wang, Qi Zhang, Xiaochen Dong

Research output: Contribution to journal › Review article › peer-review

81 Scopus citations

Abstract

Inspired by the slight acidic microenvironment, a variety of pH-responsive nanomaterials are designed for highly effective antibacterial therapy by improving the ability of drug penetration and retention to enhance the therapeutic efficacy of phototherapy or control surface adhesion. This review summarizes the common pH-responsive modes and highlights the recent and potential applications of pH-responsive nanomaterials in anti-infective therapy. Finally, the challenges and prospects of pH-responsive nanomaterials in clinical transformation are discussed.

Original language	English
Pages (from-to)	10700-10711
Number of pages	12
Journal	Journal of Materials Chemistry B
Volume	8
Issue number	47
DOIs	https://doi.org/10.1039/d0tb02177f
State	Published - 21 Dec 2020

Access to Document

10.1039/d0tb02177f

Cite this

@article{4ebefb1b744449e8b733cc8081df52e8,

title = "Recent advances in pH-responsive nanomaterials for anti-infective therapy",

abstract = "Inspired by the slight acidic microenvironment, a variety of pH-responsive nanomaterials are designed for highly effective antibacterial therapy by improving the ability of drug penetration and retention to enhance the therapeutic efficacy of phototherapy or control surface adhesion. This review summarizes the common pH-responsive modes and highlights the recent and potential applications of pH-responsive nanomaterials in anti-infective therapy. Finally, the challenges and prospects of pH-responsive nanomaterials in clinical transformation are discussed.",

author = "Xinyi Lv and Jiayao Zhang and Dongliang Yang and Jinjun Shao and Wenjun Wang and Qi Zhang and Xiaochen Dong",

note = "Publisher Copyright: {\textcopyright} 2020 The Royal Society of Chemistry.",

year = "2020",

month = dec,

day = "21",

doi = "10.1039/d0tb02177f",

language = "英语",

volume = "8",

pages = "10700--10711",

journal = "Journal of Materials Chemistry B",

issn = "2050-750X",

publisher = "Royal Society of Chemistry",

number = "47",

}

TY - JOUR

T1 - Recent advances in pH-responsive nanomaterials for anti-infective therapy

AU - Lv, Xinyi

AU - Zhang, Jiayao

AU - Yang, Dongliang

AU - Shao, Jinjun

AU - Wang, Wenjun

AU - Zhang, Qi

AU - Dong, Xiaochen

PY - 2020/12/21

Y1 - 2020/12/21

N2 - Inspired by the slight acidic microenvironment, a variety of pH-responsive nanomaterials are designed for highly effective antibacterial therapy by improving the ability of drug penetration and retention to enhance the therapeutic efficacy of phototherapy or control surface adhesion. This review summarizes the common pH-responsive modes and highlights the recent and potential applications of pH-responsive nanomaterials in anti-infective therapy. Finally, the challenges and prospects of pH-responsive nanomaterials in clinical transformation are discussed.

AB - Inspired by the slight acidic microenvironment, a variety of pH-responsive nanomaterials are designed for highly effective antibacterial therapy by improving the ability of drug penetration and retention to enhance the therapeutic efficacy of phototherapy or control surface adhesion. This review summarizes the common pH-responsive modes and highlights the recent and potential applications of pH-responsive nanomaterials in anti-infective therapy. Finally, the challenges and prospects of pH-responsive nanomaterials in clinical transformation are discussed.

UR - http://www.scopus.com/inward/record.url?scp=85098079983&partnerID=8YFLogxK

U2 - 10.1039/d0tb02177f

DO - 10.1039/d0tb02177f

M3 - 文献综述

C2 - 33140806

AN - SCOPUS:85098079983

SN - 2050-750X

VL - 8

SP - 10700

EP - 10711

JO - Journal of Materials Chemistry B

JF - Journal of Materials Chemistry B

IS - 47

ER -

Recent advances in pH-responsive nanomaterials for anti-infective therapy

Abstract

Access to Document

Other files and links

Fingerprint

Cite this