Regioselective synthesis of 6-nitroindole derivatives from enaminones and nitroaromatic compounds: Via transition metal-free C-C and C-N bond formation

Danhua Ge; Li Wen Sun; Zi Lun Yu; Xin Long Luo; Pei Xu; Zhi Liang Shen

doi:10.1039/d1ob02443d

Regioselective synthesis of 6-nitroindole derivatives from enaminones and nitroaromatic compounds: Via transition metal-free C-C and C-N bond formation

Danhua Ge, Li Wen Sun, Zi Lun Yu, Xin Long Luo, Pei Xu, Zhi Liang Shen

School of Chemistry and Moleculai Engineering

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Few methods are known for the synthesis of nitroindole derivatives. A simple and practical Cs2CO3-promoted method for the synthesis of 6-nitroindole derivatives from enaminones and nitroaromatic compounds has been developed. Two new C-C and C-N bonds were formed in a highly regioselective manner under transition metal-free conditions.

Original language	English
Pages (from-to)	1493-1499
Number of pages	7
Journal	Organic and Biomolecular Chemistry
Volume	20
Issue number	7
DOIs	https://doi.org/10.1039/d1ob02443d
State	Published - 21 Feb 2022

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title = "Regioselective synthesis of 6-nitroindole derivatives from enaminones and nitroaromatic compounds: Via transition metal-free C-C and C-N bond formation",

abstract = "Few methods are known for the synthesis of nitroindole derivatives. A simple and practical Cs2CO3-promoted method for the synthesis of 6-nitroindole derivatives from enaminones and nitroaromatic compounds has been developed. Two new C-C and C-N bonds were formed in a highly regioselective manner under transition metal-free conditions.",

author = "Danhua Ge and Sun, {Li Wen} and Yu, {Zi Lun} and Luo, {Xin Long} and Pei Xu and Shen, {Zhi Liang}",

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T1 - Regioselective synthesis of 6-nitroindole derivatives from enaminones and nitroaromatic compounds

T2 - Via transition metal-free C-C and C-N bond formation

AU - Ge, Danhua

AU - Sun, Li Wen

AU - Yu, Zi Lun

AU - Luo, Xin Long

AU - Xu, Pei

AU - Shen, Zhi Liang

PY - 2022/2/21

Y1 - 2022/2/21

N2 - Few methods are known for the synthesis of nitroindole derivatives. A simple and practical Cs2CO3-promoted method for the synthesis of 6-nitroindole derivatives from enaminones and nitroaromatic compounds has been developed. Two new C-C and C-N bonds were formed in a highly regioselective manner under transition metal-free conditions.

AB - Few methods are known for the synthesis of nitroindole derivatives. A simple and practical Cs2CO3-promoted method for the synthesis of 6-nitroindole derivatives from enaminones and nitroaromatic compounds has been developed. Two new C-C and C-N bonds were formed in a highly regioselective manner under transition metal-free conditions.

UR - http://www.scopus.com/inward/record.url?scp=85124636516&partnerID=8YFLogxK

U2 - 10.1039/d1ob02443d

DO - 10.1039/d1ob02443d

M3 - 文章

C2 - 35107115

AN - SCOPUS:85124636516

SN - 1477-0520

VL - 20

SP - 1493

EP - 1499

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 7

ER -

Regioselective synthesis of 6-nitroindole derivatives from enaminones and nitroaromatic compounds: Via transition metal-free C-C and C-N bond formation

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