TY - JOUR
T1 - Solubility and Solution Thermodynamics of Gibberellin A4 in Different Organic Solvents from 278.15 K to 333.15 K
AU - Wu, Gang
AU - Hu, Yonghong
AU - Gu, Pengfei
AU - Yang, Wenge
AU - Ding, Zhiwen
AU - Wang, Chunxiao
AU - Qian, Yonggen
N1 - Publisher Copyright:
© 2015 American Chemical Society.
PY - 2015/7/9
Y1 - 2015/7/9
N2 - Data on corresponding solid-liquid equilibrium of Gibberellin A4 (GA4) in different solvents is essential for a preliminary study of industrial applications. In this paper, the solid-liquid equilibrium of GA4 in water, methanol, ethanol, isopropanol, 1-butanol, acetonitrile, acetone, and ethyl acetate was explored in the temperatures (from 278.15 K to 333.15 K) under atmosphere pressure. For the temperature range investigated, the solubility of GA4 in the solvents increased with increasing temperature. From 278.15 K to 333.15 K, the solubility of GA4 in isopropanol is superior to other selected solvents. The modified Apelblat model, the Buchowski-Ksiazaczak λh model, and the ideal model were adopted to describe and predict the change tendency of solubility. Computational results showed that the modified Apelblat model has advantages than the other two models. In addition, the calculated thermodynamic parameters indicated that in each studied solvent the dissolution of GA4 is endothermic, nonspontaneous, and an entropy-driven process.
AB - Data on corresponding solid-liquid equilibrium of Gibberellin A4 (GA4) in different solvents is essential for a preliminary study of industrial applications. In this paper, the solid-liquid equilibrium of GA4 in water, methanol, ethanol, isopropanol, 1-butanol, acetonitrile, acetone, and ethyl acetate was explored in the temperatures (from 278.15 K to 333.15 K) under atmosphere pressure. For the temperature range investigated, the solubility of GA4 in the solvents increased with increasing temperature. From 278.15 K to 333.15 K, the solubility of GA4 in isopropanol is superior to other selected solvents. The modified Apelblat model, the Buchowski-Ksiazaczak λh model, and the ideal model were adopted to describe and predict the change tendency of solubility. Computational results showed that the modified Apelblat model has advantages than the other two models. In addition, the calculated thermodynamic parameters indicated that in each studied solvent the dissolution of GA4 is endothermic, nonspontaneous, and an entropy-driven process.
UR - http://www.scopus.com/inward/record.url?scp=84937402663&partnerID=8YFLogxK
U2 - 10.1021/acs.jced.5b00190
DO - 10.1021/acs.jced.5b00190
M3 - 文章
AN - SCOPUS:84937402663
SN - 0021-9568
VL - 60
SP - 2104
EP - 2109
JO - Journal of Chemical and Engineering Data
JF - Journal of Chemical and Engineering Data
IS - 7
ER -