Solvent-free copper-catalyzed N-arylation of amino alcohols and diamines with aryl halides

Huiqing Yin, Ming Jin, Wei Chen, Chen Chen, Likang Zheng, Ping Wei, Shiqing Han

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

A simple and mild method for the coupling of aryl halides with amino alcohols and diamines is described. The reactions can be performed under ligand-free and solvent-free conditions, and generate the products in good yield.

Original languageEnglish
Pages (from-to)1265-1270
Number of pages6
JournalTetrahedron Letters
Volume53
Issue number10
DOIs
StatePublished - 7 Mar 2012

Keywords

  • Amino alcohols
  • Copper-catalyzed
  • Diamines
  • N-arylation
  • Solvent-free

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