Study of the nano-size silica sol-gel film as the matrix of chemically modified electrode

This paper reports a new method to make the sol-gel film from silicate. It provided more profitable conditions than hydrolysis of alkoxyl silane to prepare the high-quality nanometers thin film. The thin film could be applied as the matrix to directly modify the molecules of methylene blue on electrode surface and kept their electrochemical activity excellently. It exhibited the remarkable catalytic activity for the oxidation of NADH or reduction of hemoglobin while severally embedding them in the sol-gel film together with methylene blue.