Sulfamic acid catalyzed direct condensation of aldehydes, amines, and TMSCN to α-aminonitriles at ambient temperature

Zhenjiang Li; Yingjie Sun; Xinghua Ren; Ping Wei; Yuhu Shi; Pingkai Ouyang

doi:10.1055/s-2007-970752

Sulfamic acid catalyzed direct condensation of aldehydes, amines, and TMSCN to α-aminonitriles at ambient temperature

Zhenjiang Li, Yingjie Sun, Xinghua Ren, Ping Wei, Yuhu Shi, Pingkai Ouyang

COLLEGE OF BIOTECHNOLOGY AND PHARMACEUTICAL ENGINEERING

Nanjing Tech University

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

A simple and efficient method has been developed for the synthesis of α-aminonitriles by a one-pot three-component condensation of aldehydes, amines, and trimethylsilyl cyanide in the presence of a catalytic amount of sulfamic acid at room temperature.

Original language	English
Pages (from-to)	803-805
Number of pages	3
Journal	Synlett
Issue number	5
DOIs	https://doi.org/10.1055/s-2007-970752
State	Published - 16 Mar 2007

Keywords

Aldehyde
Amine
Sulfamic acid
Three-component reaction
α-aminonitrile

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10.1055/s-2007-970752

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title = "Sulfamic acid catalyzed direct condensation of aldehydes, amines, and TMSCN to α-aminonitriles at ambient temperature",

abstract = "A simple and efficient method has been developed for the synthesis of α-aminonitriles by a one-pot three-component condensation of aldehydes, amines, and trimethylsilyl cyanide in the presence of a catalytic amount of sulfamic acid at room temperature.",

keywords = "Aldehyde, Amine, Sulfamic acid, Three-component reaction, α-aminonitrile",

author = "Zhenjiang Li and Yingjie Sun and Xinghua Ren and Ping Wei and Yuhu Shi and Pingkai Ouyang",

year = "2007",

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AU - Li, Zhenjiang

AU - Sun, Yingjie

AU - Ren, Xinghua

AU - Wei, Ping

AU - Shi, Yuhu

AU - Ouyang, Pingkai

PY - 2007/3/16

Y1 - 2007/3/16

N2 - A simple and efficient method has been developed for the synthesis of α-aminonitriles by a one-pot three-component condensation of aldehydes, amines, and trimethylsilyl cyanide in the presence of a catalytic amount of sulfamic acid at room temperature.

AB - A simple and efficient method has been developed for the synthesis of α-aminonitriles by a one-pot three-component condensation of aldehydes, amines, and trimethylsilyl cyanide in the presence of a catalytic amount of sulfamic acid at room temperature.

KW - Aldehyde

KW - Amine

KW - Sulfamic acid

KW - Three-component reaction

KW - α-aminonitrile

UR - http://www.scopus.com/inward/record.url?scp=33947711966&partnerID=8YFLogxK

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DO - 10.1055/s-2007-970752

M3 - 文章

AN - SCOPUS:33947711966

SN - 0936-5214

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EP - 805

JO - Synlett

JF - Synlett

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ER -

Sulfamic acid catalyzed direct condensation of aldehydes, amines, and TMSCN to α-aminonitriles at ambient temperature

Abstract

Keywords

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