Synthesis of a new rigid bicyclic AMPP Ligand (TIAMPP) and application in asymmetric hydrogenation

Da Chun Gong, Ping Wei, Hua Zhou, Xiong Liang Wang, Ping Kai Ouyang

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The new rigid bicyclic AMPP((S)-TIAMPP) has been synthesized from the corresponding Ticol and Ph2PCl. The application of (S)-TIAMPP in Rh-catalyzed asymmetric hydrogenation of α-dehydroamino acids derivatives has been examined. Up to 93% ee was obtained.

Original languageEnglish
Pages (from-to)1169-1172
Number of pages4
JournalChinese Chemical Letters
Volume16
Issue number9
DOIs
StatePublished - Sep 2005

Keywords

  • (S)-TIAMPP
  • Asymmetric hydrogenation
  • Synthesis

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