Synthesis of multi-substituted pyrroles using enamides and alkynes catalyzed by Pd(OAc)2 with molecular oxygen as an oxidant

Yun He Xu; Tao He; Qiu Chi Zhang; Teck Peng Loh

doi:10.1039/c3cc49683j

Synthesis of multi-substituted pyrroles using enamides and alkynes catalyzed by Pd(OAc)₂ with molecular oxygen as an oxidant

Yun He Xu, Tao He, Qiu Chi Zhang, Teck Peng Loh

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

A cyclization reaction between enamides and alkynes catalyzed by palladium(ii) acetate is described. In this method, the molecular oxygen serves as an efficient oxidant for the Pd(II)/Pd(0) catalytic cycle. The simple reaction conditions permit this methodology to be used as a general tool for the preparation of multi-substituted pyrroles.

Original language	English
Pages (from-to)	2784-2786
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	21
DOIs	https://doi.org/10.1039/c3cc49683j
State	Published - 13 Feb 2014
Externally published	Yes

Access to Document

10.1039/c3cc49683j

Cite this

@article{6bd8728ea5bc45efa31ab79c4b31796a,

title = "Synthesis of multi-substituted pyrroles using enamides and alkynes catalyzed by Pd(OAc)2 with molecular oxygen as an oxidant",

abstract = "A cyclization reaction between enamides and alkynes catalyzed by palladium(ii) acetate is described. In this method, the molecular oxygen serves as an efficient oxidant for the Pd(II)/Pd(0) catalytic cycle. The simple reaction conditions permit this methodology to be used as a general tool for the preparation of multi-substituted pyrroles.",

author = "Xu, {Yun He} and Tao He and Zhang, {Qiu Chi} and Loh, {Teck Peng}",

year = "2014",

month = feb,

day = "13",

doi = "10.1039/c3cc49683j",

language = "英语",

volume = "50",

pages = "2784--2786",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "21",

}

TY - JOUR

T1 - Synthesis of multi-substituted pyrroles using enamides and alkynes catalyzed by Pd(OAc)2 with molecular oxygen as an oxidant

AU - Xu, Yun He

AU - He, Tao

AU - Zhang, Qiu Chi

AU - Loh, Teck Peng

PY - 2014/2/13

Y1 - 2014/2/13

N2 - A cyclization reaction between enamides and alkynes catalyzed by palladium(ii) acetate is described. In this method, the molecular oxygen serves as an efficient oxidant for the Pd(II)/Pd(0) catalytic cycle. The simple reaction conditions permit this methodology to be used as a general tool for the preparation of multi-substituted pyrroles.

AB - A cyclization reaction between enamides and alkynes catalyzed by palladium(ii) acetate is described. In this method, the molecular oxygen serves as an efficient oxidant for the Pd(II)/Pd(0) catalytic cycle. The simple reaction conditions permit this methodology to be used as a general tool for the preparation of multi-substituted pyrroles.

UR - http://www.scopus.com/inward/record.url?scp=84894121663&partnerID=8YFLogxK

U2 - 10.1039/c3cc49683j

DO - 10.1039/c3cc49683j

M3 - 文章

C2 - 24481210

AN - SCOPUS:84894121663

SN - 1359-7345

VL - 50

SP - 2784

EP - 2786

JO - Chemical Communications

JF - Chemical Communications

IS - 21

ER -

Synthesis of multi-substituted pyrroles using enamides and alkynes catalyzed by Pd(OAc)₂ with molecular oxygen as an oxidant

Abstract

Access to Document

Other files and links

Fingerprint

Cite this