Abstract
The diversity of stress responses and survival strategies evolved by microorganism enables them to survive and reproduce in a multitude of harsh environments, whereas the discovery of the underlying resistance genes or mechanisms laid the foundation for the directional enhancement of microbial tolerance to abiotic stresses encountered in industrial applications. Many biological techniques have been developed for improving the stress resistance of industrial microorganisms, which greatly benefited the bacteria on which industrial production is based. This review introduces the main techniques for enhancing the resistance of microorganisms to abiotic stresses, including evolutionary engineering, metabolic engineering, and process engineering, developed in recent years. In addition, we also discuss problems that are still present in this area and offer directions for future research.
| Original language | English |
|---|---|
| Pages (from-to) | 73-81 |
| Number of pages | 9 |
| Journal | Biotechnology and Applied Biochemistry |
| Volume | 67 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1 Jan 2020 |
Keywords
- abiotic stresses
- evolutionary engineering
- improvement of microbial tolerance
- metabolic engineering
- process engineering