The current status of biotechnological production and the application of a novel antioxidant ergothioneine

Yiwen Han, Xiuyang Tang, Yuting Zhang, Xuechao Hu, Lu Jing Ren

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations

Abstract

Ergothioneine is a sulfur-containing histidine derivative, that possessesexcellent antioxidant activity and has been used in the food and cosmetics industries. It plays a significant role in anti-aging and the prevention of various diseases. This review will briefly introduce the functions and applications of ergothioneine, elaborate the biosynthetic pathways of ergothioneine and describe several strategies to increase the production of ergothioneine. Then the efficient extraction and detection methods of ergothioneine will be presented. Finally, several proposals are put forward to increase the yield of ergothioneine, and the development prospects of ergothioneine will be discussed.

Original languageEnglish
Pages (from-to)580-593
Number of pages14
JournalCritical Reviews in Biotechnology
Volume41
Issue number4
DOIs
StatePublished - 2021

Keywords

  • Ergothioneine
  • antioxidant
  • biosynthesis
  • fermentation
  • metabolic engineering
  • mushroom

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