Thermodynamic analysis and correlation of solid-liquid equilibrium of hyodeoxycholic acid in ethanol + (acetone, ethyl acetate) binary solvent mixtures

Yang Yang; Yang Cao; Yonghong Hu; Qi Zhang; Wenge Yang; Fei Shen

doi:10.1016/j.molliq.2015.07.005

Thermodynamic analysis and correlation of solid-liquid equilibrium of hyodeoxycholic acid in ethanol + (acetone, ethyl acetate) binary solvent mixtures

Yang Yang, Yang Cao, Yonghong Hu, Qi Zhang, Wenge Yang, Fei Shen

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Abstract Data on corresponding solid-liquid equilibrium of hyodeoxycholic acid (HDCA) are essential for a preliminary study of industrial applications. In this paper, we focused on solubility and solution thermodynamics of HDCA. By gravimetric method, the solubility of HDCA was measured in ethanol + (acetone, ethyl acetate) binary solvent mixtures from 278.15 K to 328.15 K under atmospheric pressure. The data of equilibrium solubility were then fitted using modified Apelblat equation, a variant of the combined nearly ideal binary solvent/Redich-Kister (CNIBS/R-K) model and Jouyban-Acree model. In addition, the thermodynamic properties of the solution process, including the Gibbs energy, enthalpy, and entropy, were calculated by the van't Hoff analysis.

Original language	English
Article number	4961
Pages (from-to)	268-274
Number of pages	7
Journal	Journal of Molecular Liquids
Volume	211
DOIs	https://doi.org/10.1016/j.molliq.2015.07.005
State	Published - 25 Jul 2015

Keywords

Apelblat equation
CNIBS/R-K
Hyodeoxycholic acid
Jouyban-Acree model
van't Hoff analysis

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10.1016/j.molliq.2015.07.005

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title = "Thermodynamic analysis and correlation of solid-liquid equilibrium of hyodeoxycholic acid in ethanol + (acetone, ethyl acetate) binary solvent mixtures",

abstract = "Abstract Data on corresponding solid-liquid equilibrium of hyodeoxycholic acid (HDCA) are essential for a preliminary study of industrial applications. In this paper, we focused on solubility and solution thermodynamics of HDCA. By gravimetric method, the solubility of HDCA was measured in ethanol + (acetone, ethyl acetate) binary solvent mixtures from 278.15 K to 328.15 K under atmospheric pressure. The data of equilibrium solubility were then fitted using modified Apelblat equation, a variant of the combined nearly ideal binary solvent/Redich-Kister (CNIBS/R-K) model and Jouyban-Acree model. In addition, the thermodynamic properties of the solution process, including the Gibbs energy, enthalpy, and entropy, were calculated by the van't Hoff analysis.",

keywords = "Apelblat equation, CNIBS/R-K, Hyodeoxycholic acid, Jouyban-Acree model, van't Hoff analysis",

author = "Yang Yang and Yang Cao and Yonghong Hu and Qi Zhang and Wenge Yang and Fei Shen",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier B.V.",

year = "2015",

month = jul,

day = "25",

doi = "10.1016/j.molliq.2015.07.005",

language = "英语",

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T1 - Thermodynamic analysis and correlation of solid-liquid equilibrium of hyodeoxycholic acid in ethanol + (acetone, ethyl acetate) binary solvent mixtures

AU - Yang, Yang

AU - Cao, Yang

AU - Hu, Yonghong

AU - Zhang, Qi

AU - Yang, Wenge

AU - Shen, Fei

PY - 2015/7/25

Y1 - 2015/7/25

N2 - Abstract Data on corresponding solid-liquid equilibrium of hyodeoxycholic acid (HDCA) are essential for a preliminary study of industrial applications. In this paper, we focused on solubility and solution thermodynamics of HDCA. By gravimetric method, the solubility of HDCA was measured in ethanol + (acetone, ethyl acetate) binary solvent mixtures from 278.15 K to 328.15 K under atmospheric pressure. The data of equilibrium solubility were then fitted using modified Apelblat equation, a variant of the combined nearly ideal binary solvent/Redich-Kister (CNIBS/R-K) model and Jouyban-Acree model. In addition, the thermodynamic properties of the solution process, including the Gibbs energy, enthalpy, and entropy, were calculated by the van't Hoff analysis.

AB - Abstract Data on corresponding solid-liquid equilibrium of hyodeoxycholic acid (HDCA) are essential for a preliminary study of industrial applications. In this paper, we focused on solubility and solution thermodynamics of HDCA. By gravimetric method, the solubility of HDCA was measured in ethanol + (acetone, ethyl acetate) binary solvent mixtures from 278.15 K to 328.15 K under atmospheric pressure. The data of equilibrium solubility were then fitted using modified Apelblat equation, a variant of the combined nearly ideal binary solvent/Redich-Kister (CNIBS/R-K) model and Jouyban-Acree model. In addition, the thermodynamic properties of the solution process, including the Gibbs energy, enthalpy, and entropy, were calculated by the van't Hoff analysis.

KW - Apelblat equation

KW - CNIBS/R-K

KW - Hyodeoxycholic acid

KW - Jouyban-Acree model

KW - van't Hoff analysis

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U2 - 10.1016/j.molliq.2015.07.005

DO - 10.1016/j.molliq.2015.07.005

M3 - 文章

AN - SCOPUS:84937889379

SN - 0167-7322

VL - 211

SP - 268

EP - 274

JO - Journal of Molecular Liquids

JF - Journal of Molecular Liquids

M1 - 4961

ER -

Thermodynamic analysis and correlation of solid-liquid equilibrium of hyodeoxycholic acid in ethanol + (acetone, ethyl acetate) binary solvent mixtures

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Keywords

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