Three-Component Reaction of p-Quinone Monoacetals, Amines and Diarylphosphine Oxides to Afford m-(Phosphinyl)anilides

Ruwei Shen; Xin Wang; Shunlin Zhang; Chao Dong; Dunru Zhu; Li Biao Han

doi:10.1002/adsc.201901421

Three-Component Reaction of p-Quinone Monoacetals, Amines and Diarylphosphine Oxides to Afford m-(Phosphinyl)anilides

Ruwei Shen, Xin Wang, Shunlin Zhang, Chao Dong, Dunru Zhu, Li Biao Han

COLLEGE OF CHEMICAL ENGINEERING

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

The three-component reaction of p-quinone monoacetals, amines and diarylphosphine oxides is developed to afford m-(diarylphosphinyl)anilides in moderate to high yields. The reaction may proceed via a process involving phospha-nucleophilic addition to an iminoquinone acetal intermediate and/or carbonyl-amine condensation with a phosphinyl enone intermediate. (Figure presented.).

Original language	English
Pages (from-to)	942-948
Number of pages	7
Journal	Advanced Synthesis and Catalysis
Volume	362
Issue number	4
DOIs	https://doi.org/10.1002/adsc.201901421
State	Published - 21 Feb 2020

Keywords

Anilides
C−P bond formation
Multicomponent reaction
Organophosphorus
Regioselectivity

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10.1002/adsc.201901421

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title = "Three-Component Reaction of p-Quinone Monoacetals, Amines and Diarylphosphine Oxides to Afford m-(Phosphinyl)anilides",

abstract = "The three-component reaction of p-quinone monoacetals, amines and diarylphosphine oxides is developed to afford m-(diarylphosphinyl)anilides in moderate to high yields. The reaction may proceed via a process involving phospha-nucleophilic addition to an iminoquinone acetal intermediate and/or carbonyl-amine condensation with a phosphinyl enone intermediate. (Figure presented.).",

keywords = "Anilides, C−P bond formation, Multicomponent reaction, Organophosphorus, Regioselectivity",

author = "Ruwei Shen and Xin Wang and Shunlin Zhang and Chao Dong and Dunru Zhu and Han, {Li Biao}",

note = "Publisher Copyright: {\textcopyright} 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim",

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T1 - Three-Component Reaction of p-Quinone Monoacetals, Amines and Diarylphosphine Oxides to Afford m-(Phosphinyl)anilides

AU - Shen, Ruwei

AU - Wang, Xin

AU - Zhang, Shunlin

AU - Dong, Chao

AU - Zhu, Dunru

AU - Han, Li Biao

PY - 2020/2/21

Y1 - 2020/2/21

N2 - The three-component reaction of p-quinone monoacetals, amines and diarylphosphine oxides is developed to afford m-(diarylphosphinyl)anilides in moderate to high yields. The reaction may proceed via a process involving phospha-nucleophilic addition to an iminoquinone acetal intermediate and/or carbonyl-amine condensation with a phosphinyl enone intermediate. (Figure presented.).

AB - The three-component reaction of p-quinone monoacetals, amines and diarylphosphine oxides is developed to afford m-(diarylphosphinyl)anilides in moderate to high yields. The reaction may proceed via a process involving phospha-nucleophilic addition to an iminoquinone acetal intermediate and/or carbonyl-amine condensation with a phosphinyl enone intermediate. (Figure presented.).

KW - Anilides

KW - C−P bond formation

KW - Multicomponent reaction

KW - Organophosphorus

KW - Regioselectivity

UR - http://www.scopus.com/inward/record.url?scp=85077057608&partnerID=8YFLogxK

U2 - 10.1002/adsc.201901421

DO - 10.1002/adsc.201901421

M3 - 文章

AN - SCOPUS:85077057608

SN - 1615-4150

VL - 362

SP - 942

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JO - Advanced Synthesis and Catalysis

JF - Advanced Synthesis and Catalysis

IS - 4

ER -

Three-Component Reaction of p-Quinone Monoacetals, Amines and Diarylphosphine Oxides to Afford m-(Phosphinyl)anilides

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Keywords

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