Three component synthesis of β-amino carbonyl compounds using indium trichloride-catalyzed one-pot Mannich-type reaction in water

Teck Peng Loh, Sarah B.K.W. Liung, Kee Leng Tan, Lin Li Wei

Research output: Contribution to journalArticlepeer-review

170 Scopus citations

Abstract

The use of indium trichloride as catalyst in a one-pot Mannich reaction in water gives high yields for the formation of β-aminoketones/esters/acids is described. The catalyst can be recycled when the reaction is complete (Loh T.-P.; Wei L.-L. Tetrahedron Lett. 1998, 39, 323). (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)3227-3237
Number of pages11
JournalTetrahedron
Volume56
Issue number20
DOIs
StatePublished - 12 May 2000
Externally publishedYes

Keywords

  • Indium trichloride
  • One-pot Mannich reaction
  • β-aminoketones

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