Transition-Metal-Catalyzed α,β-Dehydrogenation of Carbonyl Compounds

Qiang Qiang Li, Peng Fei Dai, Jian Ping Qu, Yan Biao Kang

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

α,β-Unsaturated compounds are one of the most important functional compounds. Due to their unique property and versatile utility, they usually occur as the key intermediates for the synthesis of pharmaceuticals and biological materials. Thus, their synthesis has attracted more attentions than before. The early approaches to α,β-unsaturated compounds are mainly about transition-metal-free methods, such as halogenation-dehydrohalogenation methods and strong oxidants methods (organosulfur, organoselenium, benzoquinone). Subsequently, palladium and the other transition-metals catalyzed dehydrogenation of carbonyl compounds appeared respectively. In this review, transition-metal-catalyzed α,β-dehydrogenation is discussed, which is categorized by functional groups.

Original languageEnglish
Article numbere202301267
JournalEuropean Journal of Organic Chemistry
Volume27
Issue number10
DOIs
StatePublished - 11 Mar 2024

Keywords

  • Saegusa-Ito oxidation
  • carbonyl
  • transition-metal-catalyzed
  • α,β-dehydrogenation
  • α,β-unsaturated

Fingerprint

Dive into the research topics of 'Transition-Metal-Catalyzed α,β-Dehydrogenation of Carbonyl Compounds'. Together they form a unique fingerprint.

Cite this