Visualization of nitroxyl in living cells by a chelated copper(II) coumarin complex

Yi Zhou; Ke Liu; Ju Ying Li; Yuan Fang; Tian Chu Zhao; Cheng Yao

doi:10.1021/ol103077q

Visualization of nitroxyl in living cells by a chelated copper(II) coumarin complex

Yi Zhou, Ke Liu, Ju Ying Li, Yuan Fang, Tian Chu Zhao, Cheng Yao

School of Chemistry and Moleculai Engineering

Nanjing Tech University

Research output: Contribution to journal › Article › peer-review

148 Scopus citations

Abstract

The coumarin-based probe Cu(II)-COT1 was successfully developed for the detection of HNO on the basis of the reduction reaction. In addition, highly selective "turn on" type fluorogenic behavior upon the addition of Angeli's salt (Na₂N₂O₃) was also applied to bioimaging in A375 cells.

Original language	English
Pages (from-to)	1290-1293
Number of pages	4
Journal	Organic Letters
Volume	13
Issue number	6
DOIs	https://doi.org/10.1021/ol103077q
State	Published - 18 Mar 2011

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10.1021/ol103077q

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title = "Visualization of nitroxyl in living cells by a chelated copper(II) coumarin complex",

abstract = "The coumarin-based probe Cu(II)-COT1 was successfully developed for the detection of HNO on the basis of the reduction reaction. In addition, highly selective {"}turn on{"} type fluorogenic behavior upon the addition of Angeli's salt (Na2N2O3) was also applied to bioimaging in A375 cells.",

author = "Yi Zhou and Ke Liu and Li, {Ju Ying} and Yuan Fang and Zhao, {Tian Chu} and Cheng Yao",

year = "2011",

month = mar,

day = "18",

doi = "10.1021/ol103077q",

language = "英语",

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journal = "Organic Letters",

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T1 - Visualization of nitroxyl in living cells by a chelated copper(II) coumarin complex

AU - Zhou, Yi

AU - Liu, Ke

AU - Li, Ju Ying

AU - Fang, Yuan

AU - Zhao, Tian Chu

AU - Yao, Cheng

PY - 2011/3/18

Y1 - 2011/3/18

N2 - The coumarin-based probe Cu(II)-COT1 was successfully developed for the detection of HNO on the basis of the reduction reaction. In addition, highly selective "turn on" type fluorogenic behavior upon the addition of Angeli's salt (Na2N2O3) was also applied to bioimaging in A375 cells.

AB - The coumarin-based probe Cu(II)-COT1 was successfully developed for the detection of HNO on the basis of the reduction reaction. In addition, highly selective "turn on" type fluorogenic behavior upon the addition of Angeli's salt (Na2N2O3) was also applied to bioimaging in A375 cells.

UR - http://www.scopus.com/inward/record.url?scp=79952578095&partnerID=8YFLogxK

U2 - 10.1021/ol103077q

DO - 10.1021/ol103077q

M3 - 文章

C2 - 21322578

AN - SCOPUS:79952578095

SN - 1523-7060

VL - 13

SP - 1290

EP - 1293

JO - Organic Letters

JF - Organic Letters

IS - 6

ER -

Visualization of nitroxyl in living cells by a chelated copper(II) coumarin complex

Abstract

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