摘要
Tetracarbon organic acids are important platform chemicals that are widely used in the food, chemical, medicine, material industries and agriculture. Compared with the traditional petrochemical process, the production of tetracarbon organic acids by microbial fermentation is more promising due to milder reaction conditions, greener process and better environmental compatibility. This review summarizes the biosynthetic pathways and metabolic mechanisms for the production of tetracarbon organic acids, and illustrates recent advances, challenges, and future perspectives in the production of tetracarbon organic acids by naturally selected or purposefully engineered strains.
| 投稿的翻译标题 | Advances in the metabolic engineering for the production of tetracarbon organic acids |
|---|---|
| 源语言 | 繁体中文 |
| 页（从-至） | 1697-1720 |
| 页数 | 24 |
| 期刊 | Shengwu Gongcheng Xuebao/Chinese Journal of Biotechnology |
| 卷 | 37 |
| 期 | 5 |
| DOI | |
| 出版状态 | 已出版 - 25 5月 2021 |
关键词
- C-4 organic acid
- Metabolic engineering
- Microbial fermentation
- Strain screening