解淀粉芽孢杆菌分子遗传操作及其应用研究进展

Bacillus amyloliquefaciens is a Generally Recognized as Safe(GRAS)strain recognized by the FDA. It has outstanding advantages in the production of industrial enzyme preparations,high molecular polymers,bulk chemicals,and green biological pesticides. In recent years,as the molecular genetic manipulation technology of B. amyloliquefaciens has become more and more mature,there has been a more urgent need for the use of the bacteria to develop microbial fermentation platform strains for use in the field of synthetic biology manufacturing. In this paper,the genetic manipulation tools,metabolic modification applications and future development prospects of B. amyloliquefaciens are reviewed in detail,which will provide reference for further promoting the innovation and development of B. amyloliquefaciens on synthetic biology technology.