TY - JOUR
T1 - 1,2,3,4-Tetrahydro-1,4-methanonaphthalene-2,3-diol
AU - Xu, Jian
AU - Xu, Hao
AU - Quan, Ji Cai
AU - Sha, Fei
AU - Yao, Cheng
PY - 2008
Y1 - 2008
N2 - The title compound, C11H12O2, is an inter-mediate in the synthesis of Varenicline, a nicotinic receptor partial agonist used to treat smoking addiction. In the crystal structure, there is an intra-molecular O - H⋯O hydrogen bond that generates an S(5) ring motif. Inter-molecular O - H⋯O hydrogen bonds form centrosymmetric dimers and also link these dimers into chains along the a axis.
AB - The title compound, C11H12O2, is an inter-mediate in the synthesis of Varenicline, a nicotinic receptor partial agonist used to treat smoking addiction. In the crystal structure, there is an intra-molecular O - H⋯O hydrogen bond that generates an S(5) ring motif. Inter-molecular O - H⋯O hydrogen bonds form centrosymmetric dimers and also link these dimers into chains along the a axis.
UR - http://www.scopus.com/inward/record.url?scp=58149469214&partnerID=8YFLogxK
U2 - 10.1107/S1600536808041068
DO - 10.1107/S1600536808041068
M3 - 文章
AN - SCOPUS:58149469214
SN - 1600-5368
VL - 65
SP - o79
JO - Acta Crystallographica Section E: Structure Reports Online
JF - Acta Crystallographica Section E: Structure Reports Online
IS - 1
ER -