A fluorescence probe for bisulfite sensing based on the bisulfite-induced binding site transfer between Zn2+ and an aminoquinoline derivate

Tingwen Wei, Fang Wang, Yahui Chen, Jian Qiang, Zhijie Zhang, Tiantian Chen, Xiaoqiang Chen

科研成果: 期刊稿件文章同行评审

21 引用 (Scopus)

摘要

A fluorescent probe is constructed to quickly and accurately detect bisulfite. The detection mechanism was considered to operate via the bisulfite, causing deprotonation of amido bond of 8-aminoquinoline derivative leading to fluorescence enhancement. The probe has a good selectivity for bisulfite over the other competitive substances such as F, Cl, Br, I, C2O4 2−, NO2 , ClO4 , OAc, PO4 3−, CO3 2−, HCO3 , HS, HSO4 , SCN, SO4 2−, S2O3 2−, Cys, Hcy and GSH. There is a good linear relationship between fluorescence intensity and the concentration of bisulfite in the range of 0–200 μM. The limit of detection was calculated to be 0.61 μM. Furthermore, the probe has also been successfully used for imaging bisulfite in living cells.

源语言英语
页(从-至)322-330
页数9
期刊Dyes and Pigments
159
DOI
出版状态已出版 - 12月 2018

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