A Near Infrared Cyanine-Based Fluorescent Probe for Highly Selectively Detecting Glutathione in Living Cells

Xiaole Sheng, Dan Chen, Meijiao Cao, Yufeng Zhang, Xie Han, Xiaoqiang Chen, Shenghua Liu, Haiyan Chen, Jun Yin

科研成果: 期刊稿件文章同行评审

30 引用 (Scopus)

摘要

Amino acids containing the thiol group play significant roles in keeping biological oxidation reduction balance. Due to the important cellular function of biothiols, it is imperative to develop efficient methods to detect biothiols in complicate biological systems. In this work, we developed a cyanine-based fluorescent probe utilizing thioether as a detecting group, which showed the fluorescent "turn-on" response towards GSH and it can be used as a biomarker to determine the cellular GSH.

源语言英语
页(从-至)594-598
页数5
期刊Chinese Journal of Chemistry
34
6
DOI
出版状态已出版 - 6月 2016

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