@article{f7709a0131f34e26944e19350b494d44,
title = "A simple oxazolidine linker for solid-phase synthesis of peptide aldehydes",
abstract = "A very simple and cheap linker has been used for solid-phase synthesis of peptide aldehydes. Protected amino acid aldehydes are immobilized on 2-Cl(trt) resin as oxazolidine formation via diethanolamine. After classical Fmoc SPPS, treatment of the resin with AcOH/DCM/H 2O (8:1:1) affords peptide aldehydes in high yield and purity.",
keywords = "2-Cl(trt) resin, Diethanolamine, Oxazolidine, Peptide aldehydes, Solid-phase synthesis",
author = "Wu Kang and Weiguo Wang and Xiaoxia Zhi and Bo Zhang and Ping Wei and Hongyan Xu",
year = "2012",
month = jan,
day = "15",
doi = "10.1016/j.bmcl.2011.11.081",
language = "英语",
volume = "22",
pages = "1187--1188",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
publisher = "Elsevier Ltd",
number = "2",
}