An asymmetric synthesis of the polyol fragment of the polyene macrolide antibiotic RK-397

Fan Fu; Teck Peng Loh

doi:10.1016/j.tetlet.2009.03.019

An asymmetric synthesis of the polyol fragment of the polyene macrolide antibiotic RK-397

Fan Fu, Teck Peng Loh

Nanyang Technological University

科研成果: 期刊稿件 › 文章 › 同行评审

19 引用（Scopus）

摘要

A highly convergent and asymmetric synthesis of the C11-C31 polyol fragment of RK-397 as a single isomer is accomplished via a catalytic enantioselective hetero-Diels-Alder reaction and an intermolecular olefin cross-metathesis as key steps.

源语言	英语
页（从-至）	3530-3533
页数	4
期刊	Tetrahedron Letters
卷	50
期	26
DOI	https://doi.org/10.1016/j.tetlet.2009.03.019
出版状态	已出版 - 1 7月 2009
已对外发布	是

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10.1016/j.tetlet.2009.03.019

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abstract = "A highly convergent and asymmetric synthesis of the C11-C31 polyol fragment of RK-397 as a single isomer is accomplished via a catalytic enantioselective hetero-Diels-Alder reaction and an intermolecular olefin cross-metathesis as key steps.",

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AB - A highly convergent and asymmetric synthesis of the C11-C31 polyol fragment of RK-397 as a single isomer is accomplished via a catalytic enantioselective hetero-Diels-Alder reaction and an intermolecular olefin cross-metathesis as key steps.

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M3 - 文章

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An asymmetric synthesis of the polyol fragment of the polyene macrolide antibiotic RK-397

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