An in situ ratiometric fluorescence immunosensor via Mn2+-triggered aggregation-induced emission transformation of levodopa fluorescent copolymer nanoparticles

Yifei Ma, Xiaoxue Liu, Naidi Yang, Changpeng Zou, Yujie Sun, Guichuan Xing, Jinhua Liu, Zhihui Xu, Fenghua Geng

科研成果: 期刊稿件文章同行评审

摘要

Herein, a direct in situ alkaline phosphatase (ALP)-labeled luminescent nanoimmunoassay platform was constructed using Mn2+-triggered aggregation-induced emission transformation of levodopa fluorescent copolymer (LFC) nanoparticles. Using cardiac troponin I (cTn I) as the model antigen, the proposed nanoimmunosensor has been applied to detect cTn I in clinical samples with satisfactory results.

源语言英语
页(从-至)6676-6680
页数5
期刊Analytical Methods
16
39
DOI
出版状态已出版 - 10 9月 2024

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