摘要
A novel calcium-catalyzed in situ dehydrative cross-coupling reaction of propargylic alcohols with 1,3-dicarbonyl compounds was developed. This catalytic system can suppress the competitive Meyer-Schuster rearrangement, control regioselectivity, and enable the desired process to occur under solvent-free conditions at room temperature with water as the only byproduct. A variety of vicinal tertiary and all-carbon quaternary centers can be obtained in high yields with broad functional group tolerance.
| 源语言 | 英语 |
|---|---|
| 页（从-至） | 5207-5211 |
| 页数 | 5 |
| 期刊 | Green Chemistry |
| 卷 | 21 |
| 期 | 19 |
| DOI | |
| 出版状态 | 已出版 - 2019 |