Cobalt-Catalyzed Carbonylative Synthesis of 4-Oxobutanoates from Formamide and Ethylene

Le Cheng Wang; Nai Xian Sun; Chang Sheng Wang; Kai Guo; Xiao Feng Wu

doi:10.1021/acs.orglett.3c02973

Cobalt-Catalyzed Carbonylative Synthesis of 4-Oxobutanoates from Formamide and Ethylene

Le Cheng Wang, Nai Xian Sun, Chang Sheng Wang, Kai Guo, Xiao Feng Wu

生物与制药工程学院

科研成果: 期刊稿件 › 文章 › 同行评审

3 引用（Scopus）

摘要

The direct concurrent installation of amide and ester groups across olefin motifs represents a powerful and promising functionalization tool in organic chemistry. Herein, a ligand-free cobalt-catalyzed four-component radical relay carbonylative difunctionalization of ethylene for the synthesis of 4-oxobutanoates has been developed. Valuable C4 building blocks were produced in a highly atom-economical fashion.

源语言	英语
页（从-至）	7417-7421
页数	5
期刊	Organic Letters
卷	25
期	40
DOI	https://doi.org/10.1021/acs.orglett.3c02973
出版状态	已出版 - 13 10月 2023

访问文件

10.1021/acs.orglett.3c02973

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{3054045d44874f55a1e77be4070671e1,

title = "Cobalt-Catalyzed Carbonylative Synthesis of 4-Oxobutanoates from Formamide and Ethylene",

abstract = "The direct concurrent installation of amide and ester groups across olefin motifs represents a powerful and promising functionalization tool in organic chemistry. Herein, a ligand-free cobalt-catalyzed four-component radical relay carbonylative difunctionalization of ethylene for the synthesis of 4-oxobutanoates has been developed. Valuable C4 building blocks were produced in a highly atom-economical fashion.",

author = "Wang, {Le Cheng} and Sun, {Nai Xian} and Wang, {Chang Sheng} and Kai Guo and Wu, {Xiao Feng}",

note = "Publisher Copyright: {\textcopyright} 2023 American Chemical Society.",

year = "2023",

month = oct,

day = "13",

doi = "10.1021/acs.orglett.3c02973",

language = "英语",

volume = "25",

pages = "7417--7421",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "40",

}

TY - JOUR

T1 - Cobalt-Catalyzed Carbonylative Synthesis of 4-Oxobutanoates from Formamide and Ethylene

AU - Wang, Le Cheng

AU - Sun, Nai Xian

AU - Wang, Chang Sheng

AU - Guo, Kai

AU - Wu, Xiao Feng

PY - 2023/10/13

Y1 - 2023/10/13

N2 - The direct concurrent installation of amide and ester groups across olefin motifs represents a powerful and promising functionalization tool in organic chemistry. Herein, a ligand-free cobalt-catalyzed four-component radical relay carbonylative difunctionalization of ethylene for the synthesis of 4-oxobutanoates has been developed. Valuable C4 building blocks were produced in a highly atom-economical fashion.

AB - The direct concurrent installation of amide and ester groups across olefin motifs represents a powerful and promising functionalization tool in organic chemistry. Herein, a ligand-free cobalt-catalyzed four-component radical relay carbonylative difunctionalization of ethylene for the synthesis of 4-oxobutanoates has been developed. Valuable C4 building blocks were produced in a highly atom-economical fashion.

UR - http://www.scopus.com/inward/record.url?scp=85175587359&partnerID=8YFLogxK

U2 - 10.1021/acs.orglett.3c02973

DO - 10.1021/acs.orglett.3c02973

M3 - 文章

C2 - 37795806

AN - SCOPUS:85175587359

SN - 1523-7060

VL - 25

SP - 7417

EP - 7421

JO - Organic Letters

JF - Organic Letters

IS - 40

ER -

Cobalt-Catalyzed Carbonylative Synthesis of 4-Oxobutanoates from Formamide and Ethylene

摘要

访问文件

其它文件与链接

指纹

引用此