Cobalt-Catalyzed Hydroxymethylation of Alkyl Halides with CO as the C1 Source

Yang Yuan, Nai Xian Sun, Chang Sheng Wang, Kai Guo, Xiao Feng Wu

科研成果: 期刊稿件文章同行评审

摘要

Herein, we developed an effective strategy for the synthesis of one-carbon-extended alcohols through cobalt-catalyzed hydroxymethylation of alkyl halides with carbon monoxide as the C1 source and cheap and environmentally friendly PMHS as the hydride source. This procedure also features a ligand-free cobalt catalyst and a broad range of functional group tolerance.

源语言英语
页(从-至)5084-5088
页数5
期刊Organic Letters
25
27
DOI
出版状态已出版 - 14 7月 2023

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