@article{4809c1ff54c94ed4b544873c476fe862,
title = "Copper-catalyzed enantioselective conjugate addition of grignard reagents to methyl 4,4,4-trifluorocrotonate: Synthesis of enantioenriched trifluoromethylated compounds",
abstract = "Copper-catalyzed enantioselective 1,4-conjugate addition of methyl 4,4,4-trifluorocrotonate with aliphatic Grignard reagents to access an asymmetric tertiary carbon center attached with a trifluoromethyl group was achieved under mild reaction conditions. The desired products could be obtained in reasonable yields and good enantioselectivities.",
keywords = "1,4-conjugate addition, 4,4,4-trifluorocrotonate, aliphatic Grignard reagents, copper catalysis",
author = "Zhang, {Li Ying} and Zhou, {Jia Hui} and Xu, {Yun He} and Loh, {Teck Peng}",
note = "Publisher Copyright: {\textcopyright} 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2015",
month = apr,
doi = "10.1002/asia.201403303",
language = "英语",
volume = "10",
pages = "844--848",
journal = "Chemistry - An Asian Journal",
issn = "1861-4728",
publisher = "John Wiley and Sons Ltd",
number = "4",
}