Copper-Catalyzed Three-Component Cascade Annulation for Divergent Syntheses of Imidazoles and Dihydroimidazoles

Gaochen Xu, Chenglong Jia, Xuemei Wang, Huan Yan, Sai Zhang, Qinghuan Wu, Ning Zhu, Jindian Duan, Kai Guo

科研成果: 期刊稿件文章同行评审

23 引用 (Scopus)

摘要

The first example of divergent N-heterocycle syntheses through a copper-catalyzed three-component reaction of α,β-unsaturated ketoximes, paraformaldehyde, and amines has been documented. In particular, this divergent synthetic strategy was achieved by controlling the reaction conditions to afford the corresponding imidazoles and dihydroimidazoles in moderate to good yields with a broad substrate scope and good functional group compatibility.

源语言英语
页(从-至)1060-1065
页数6
期刊Organic Letters
24
4
DOI
出版状态已出版 - 4 2月 2022

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