Current advances in organic acid production from organic wastes by using microbial co-cultivation systems

The microbial production of organic acids has become a rapidly developing field due to their increasing global market. Recently, research has transitioned towards employing synthetic microbial consortia for organic acid production. Compared with pure cultures, microbial co-cultures can perform more complex functions and endure more changeable environments. Accordingly, microbial co-cultivation technologies for organic acid production have been adopted to fulfill the requirements for the utilization of a wider range of substrates for a higher product yield. Here, we have summarized current advances towards organic acid production from different substrates by using microbial co-cultivation technologies. Furthermore, the construction mechanism of the microbial co-cultivation systems was also analyzed and compared.