@inproceedings{74883bdc9a794e8eacf35d93ad8081d9,
title = "Design, synthesis and biological evaluation of Sunitinib analogues to improve aqueous solubility",
abstract = "In order to improve aqueous solubility of Sunitinib, based on the structure-activity relationship, four analogues were designed and synthesized. The obtained structures were identified by 1H NMR, MS and elemental analysis. In vitro evaluation of antitumor bioactivity was performed by MTT method. All of synthesized compounds showed antitumor activities, especially, compounds A1, which were better than or equal to the antitumor activity of positive control.",
keywords = "Activity, Analogues, Antitumor, Synthesis",
author = "Chen, {Ke Tao} and Zheng Fang and Zhao Yang and Kai Guo",
year = "2013",
doi = "10.4028/www.scientific.net/AMR.749.350",
language = "英语",
isbn = "9783037857557",
series = "Advanced Materials Research",
pages = "350--353",
booktitle = "Bio-Medical Materials and Engineering",
note = "2013 International Conference on Bio-Medical Materials and Engineering, ICBME 2013 ; Conference date: 26-03-2013 Through 27-03-2013",
}