Direct Substitution of Secondary and Tertiary Alcohols to Generate Sulfones under Catalyst- and Additive-Free Conditions

Yanan Liu, Peizhong Xie, Zuolian Sun, Xiangyang Wo, Cuiqing Gao, Weishan Fu, Teck Peng Loh

科研成果: 期刊稿件文章同行评审

32 引用 (Scopus)

摘要

An environmentally benign protocol that affords propargylic sulfones containing highly congested carbon centers from easily accessible alcohols and sulfinic acids with water as the only byproduct is reported. The reaction proceeded via an in situ dehydrative cross-coupling process by taking advantage of the synergetic actions of multiple hydrogen bonds rather than relying on an external catalyst and/or additives to achieve high product distribution.

源语言英语
页(从-至)5353-5356
页数4
期刊Organic Letters
20
17
DOI
出版状态已出版 - 7 9月 2018

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