Direct synthesis of water-tolerant alkyl indium reagents and their application in palladium-catalyzed couplings with aryl halides

Zhi Liang Shen, Kelvin Kau Kiat Goh, Yong Sheng Yang, Yin Chang Lai, Colin Hong An Wong, Hao Lun Cheong, Teck Peng Loh

科研成果: 期刊稿件文章同行评审

49 引用 (Scopus)

摘要

A direct result: Alkyl indium reagents are synthesized by the insertion of indium into alkyl halide mediated by CuCl. The synthetic utility of these reagents is demonstrated by their palladium-catalyzed coupling with aryl halides (see scheme). The reagents are compatible with various functional groups, and this makes the protocol generally useful in organic synthesis. DMA=N,N-dimethylacetamide, TBS=tert-butyldimethylsilyl.

源语言英语
页(从-至)511-514
页数4
期刊Angewandte Chemie - International Edition
50
2
DOI
出版状态已出版 - 10 1月 2011
已对外发布

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