Divergent Metal-Free [4 + 2] Cascade Reaction of 1-Indanylidenemalononitrile with 3-Benzylidenebenzofuran-2(3 H)-one: Access to Spiro-dihydrofluorene-benzofuranone and Axially Chiral Fluorenylamine-phenol Derivatives

Ran Li, Lei Yao, Yan Bo Wang, Jun Yan Zhu, Lixiong Zhang, Ji Ya Fu, Chuan Bao Zhang, Lili Zhao

科研成果: 期刊稿件文章同行评审

6 引用 (Scopus)

摘要

An efficient cascade reaction of 1-indanylidenemalononitrile with 3-benzylidenebenzofuran-2(3H)-one divergently promoted by DABCO or chiral organocatalyst was developed under mild reaction conditions, and various spiro-dihydrofluorene-benzofuranones were produced in gratifying results, respectively. It is worth noting that both the spiro and axially chiral products can be obtained by tuning the reaction conditions. The mechanism of the transformation was also studied by quantum chemical calculations.

源语言英语
页(从-至)5611-5615
页数5
期刊Organic Letters
23
15
DOI
出版状态已出版 - 6 8月 2021

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