Efficient synthesis of ponasterone A by recombinant Escherichia coli harboring the glycosyltransferase GTBP1 with in situ product removal

Bingfeng Li, Xuejun He, Bo Fan, Jianlin Chu, Bingfang He

科研成果: 期刊稿件文章同行评审

3 引用 (Scopus)

摘要

A glycosyltransferase GTBP1 from Bacillus pumilus BF1 was isolated. Efficient production of ponasterone A was achieved by the recombinant E. coli/gtBP1 in a biphasic system with a molar yield of 92.7%. This in situ product removal provided the "driving force" for shifting the reaction equilibrium towards the synthesis of the product.

源语言英语
页(从-至)23027-23029
页数3
期刊RSC Advances
7
37
DOI
出版状态已出版 - 2017

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