TY - JOUR
T1 - Electrooxidative 1,3-Oxo/Carboamination of Arylcyclopropanes
AU - Chen, Ziyan
AU - Zhao, Shuaishuai
AU - Wang, Tiantian
AU - Xue, Fei
AU - Zhu, Chuan
AU - Yue, Yanni
AU - Feng, Chao
N1 - Publisher Copyright:
© 2024 American Chemical Society.
PY - 2024/9/6
Y1 - 2024/9/6
N2 - Herein, the work demonstrates an electrochemically paired electrolysis approach facilitating the efficient achievement of the electrooxidative 1,3-oxo/carboamination of arylcyclopropanes under mild conditions. The formation of 1,3-arylamination of arylcyclopropanes involves commercially available amine redox mediators through a radical-radical process. In addition, the successful execution of β-amino ketones also occurs under atmospheric conditions. The control experiments supported the existence of key benzylic radical intermediates in the reaction pathway.
AB - Herein, the work demonstrates an electrochemically paired electrolysis approach facilitating the efficient achievement of the electrooxidative 1,3-oxo/carboamination of arylcyclopropanes under mild conditions. The formation of 1,3-arylamination of arylcyclopropanes involves commercially available amine redox mediators through a radical-radical process. In addition, the successful execution of β-amino ketones also occurs under atmospheric conditions. The control experiments supported the existence of key benzylic radical intermediates in the reaction pathway.
UR - http://www.scopus.com/inward/record.url?scp=105001590293&partnerID=8YFLogxK
U2 - 10.1021/acs.joc.4c01175
DO - 10.1021/acs.joc.4c01175
M3 - 文章
AN - SCOPUS:105001590293
SN - 0022-3263
VL - 89
SP - 12769
EP - 12774
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
IS - 17
ER -