Enantioselective Michael addition of dicyanoolefins to α,β- unsaturated aldehydes in aqueous medium

Jun Lu, Feng Liu, Teck Peng Loh

科研成果: 期刊稿件文章同行评审

54 引用 (Scopus)

摘要

A pool of water-compatible catalysts, namely dialkyl-(S)-prolinols, has been developed for the enantioselective direct vinylogous Michael addition reaction of vinylmalononitriles to α,β-unsaturated aldehydes in aqueous medium. In many cases, the products can be obtained in almost optically pure form (>96% ee) after a single recrystallization.

源语言英语
页(从-至)1781-1784
页数4
期刊Advanced Synthesis and Catalysis
350
11-12
DOI
出版状态已出版 - 4 8月 2008
已对外发布

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