摘要
A pool of water-compatible catalysts, namely dialkyl-(S)-prolinols, has been developed for the enantioselective direct vinylogous Michael addition reaction of vinylmalononitriles to α,β-unsaturated aldehydes in aqueous medium. In many cases, the products can be obtained in almost optically pure form (>96% ee) after a single recrystallization.
源语言 | 英语 |
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页(从-至) | 1781-1784 |
页数 | 4 |
期刊 | Advanced Synthesis and Catalysis |
卷 | 350 |
期 | 11-12 |
DOI | |
出版状态 | 已出版 - 4 8月 2008 |
已对外发布 | 是 |