Fluorescence turn-on detection of hypochlorous acid via HOCl-promoted dihydrofluorescein-ether oxidation and its application in vivo

Yi Zhou; Ju Ying Li; Kai Hui Chu; Ke Liu; Cheng Yao

doi:10.1039/c2cc30265a

Fluorescence turn-on detection of hypochlorous acid via HOCl-promoted dihydrofluorescein-ether oxidation and its application in vivo

Yi Zhou, Ju Ying Li, Kai Hui Chu, Ke Liu, Cheng Yao

化学与分子工程学院

科研成果: 期刊稿件 › 文章 › 同行评审

123 引用（Scopus）

摘要

We report three new water-soluble dihydrofluorescein-ether probes FCN1, FCN2 and FCN3 for the detection of hypochlorous acid (HOCl), which were designed on the basis of a specific HOCl-promoted oxidation reaction. This work also provided a useful method to monitor the accumulated HOCl in specific organelles using a zebrafish model.

源语言	英语
页（从-至）	4677-4679
页数	3
期刊	Chemical Communications
卷	48
期	39
DOI	https://doi.org/10.1039/c2cc30265a
出版状态	已出版 - 18 4月 2012

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AU - Yao, Cheng

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AB - We report three new water-soluble dihydrofluorescein-ether probes FCN1, FCN2 and FCN3 for the detection of hypochlorous acid (HOCl), which were designed on the basis of a specific HOCl-promoted oxidation reaction. This work also provided a useful method to monitor the accumulated HOCl in specific organelles using a zebrafish model.

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Fluorescence turn-on detection of hypochlorous acid via HOCl-promoted dihydrofluorescein-ether oxidation and its application in vivo

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