@article{92cee14300754ab48ab0877ccde75b97,
title = "Generation of stereodefined (Z)-3,4-dihydronaphthalen-1(2H)-ones via copper-catalyzed annulation-cyanotrifluoromethylation of 1,7-enynes",
abstract = "A new three-component strategy for the copper-catalyzed annulation–cyanotrifluoromethylation of easily available 1,7-enynes with Togni's reagent and TMSCN is developed. The reaction proceeds smoothly under mild conditions, providing a rapid and concise access to a wide range of stereodefined (Z)-3,4-dihydronaphthalen-1(2H)-ones with a quaternary carbon center in generally good yields. The protocol enjoys wide substrate scope regarding 1,7-enynes, high functional group tolerance and complete stereoselectivity.",
keywords = "1,7-Enynes, 3,4-Dihydronaphthalen-1(2H)-ones, Copper catalysis, Cyanotrifluoromethylation, Radical annulation",
author = "Ji, {Wen Zhe} and Shi, {Hao Nan} and Hao, {Wen Juan} and Ping Wei and Tu, {Shu Jiang} and Bo Jiang",
note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd",
year = "2021",
month = feb,
day = "2",
doi = "10.1016/j.tetlet.2020.152722",
language = "英语",
volume = "64",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Ltd",
}