Genetic tool development and systemic regulation in biosynthetic technology

Zhongxue Dai, Shangjie Zhang, Qiao Yang, Wenming Zhang, Xiujuan Qian, Weiliang Dong, Min Jiang, Fengxue Xin

科研成果: 期刊稿件文献综述同行评审

29 引用 (Scopus)

摘要

With the increased development in research, innovation, and policy interest in recent years, biosynthetic technology has developed rapidly, which combines engineering, electronics, computer science, mathematics, and other disciplines based on classical genetic engineering and metabolic engineering. It gives a wider perspective and a deeper level to perceive the nature of life via cell mechanism, regulatory networks, or biological evolution. Currently, synthetic biology has made great breakthrough in energy, chemical industry, and medicine industries, particularly in the programmable genetic control at multiple levels of regulation to perform designed goals. In this review, the most advanced and comprehensive developments achieved in biosynthetic technology were represented, including genetic engineering as well as synthetic genomics. In addition, the superiority together with the limitations of the current genome-editing tools were summarized.

源语言英语
文章编号152
期刊Biotechnology for Biofuels
11
1
DOI
出版状态已出版 - 1 6月 2018

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