Highly practical oxidation of benzylic alcohol in continuous-flow system with metal-free catalyst

Chengkou Liu, Zheng Fang, Zhao Yang, Qingwen Li, Shiyu Guo, Kai Zhang, Pingkai Ouyang, Kai Guo

科研成果: 期刊稿件文章同行评审

16 引用 (Scopus)

摘要

Oxidation of benzylic alcohol to ketone or aldehyde is one of the most challenging reactions in terms of green chemistry. We report herein that employing H2O2, catalytic amount of Br- and acid in continuous-flow system to realize oxidation of benzylic alcohols with broad substrate scope and high selectivity. More importantly, no over oxidation to acid was obtained and it showed higher selectivity to 2° hydroxyl groups rather than 1°.

源语言英语
页(从-至)5973-5976
页数4
期刊Tetrahedron Letters
56
44
DOI
出版状态已出版 - 28 10月 2015

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