Highly regio- and stereoselective: Trans -iodofluorination of ynamides enabling the synthesis of (E)-α-fluoro-β-iodoenamides

Yang Xi, Guohao Zhu, Luning Tang, Shihan Ma, Dongming Zhang, Rong Zhang, Guangke He, Hongjun Zhu

科研成果: 期刊稿件文章同行评审

14 引用 (Scopus)

摘要

A highly regio- and stereoselective trans-iodofluorination reaction of ynamides with NIS and Et3N·3HF has been achieved, affording (E)-α-fluoro-β-iodoenamides in moderate to good yields. The reaction proceeds under mild reaction conditions and exhibits good functional group compatibility.

源语言英语
页(从-至)7218-7226
页数9
期刊Organic and Biomolecular Chemistry
15
34
DOI
出版状态已出版 - 2017

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