Iron-catalyzed [4 + 2] annulation of α,β-unsaturated ketoxime acetates with enaminones toward functionalized pyridines

Jindian Duan, Gaochen Xu, Binsen Rong, Huan Yan, Sai Zhang, Qinghuan Wu, Ning Zhu, Kai Guo

科研成果: 期刊稿件文章同行评审

31 引用 (Scopus)

摘要

The iron-catalyzed [4 ​+ ​2] annulation of α,β-unsaturated ketoxime acetates with enaminones has been developed, providing efficient access to highly substituted pyridines in moderate to good yields. Notable features of the present strategy include low-cost catalytic system, simple and mild reaction condition and wide substrate scope. Mechanistic studies reveal that FeCl2 may directly serve as a Lewis acid to activate the α,β-unsaturated ketoxime acetates for the nucleophilic addition.

源语言英语
页(从-至)237-240
页数4
期刊Green Synthesis and Catalysis
2
2
DOI
出版状态已出版 - 5月 2021

指纹

探究 'Iron-catalyzed [4 + 2] annulation of α,β-unsaturated ketoxime acetates with enaminones toward functionalized pyridines' 的科研主题。它们共同构成独一无二的指纹。

引用此