Lactol-ene reaction: An efficient access to the synthesis of 22R,25-dihydroxy steroid side chains

Koichi Mikami; Hiroyuki Kishino; Hiroyuki Matsueda; Teck Peng Loh

doi:10.1055/s-1993-22504

Lactol-ene reaction: An efficient access to the synthesis of 22R,25-dihydroxy steroid side chains

Koichi Mikami, Hiroyuki Kishino, Hiroyuki Matsueda, Teck Peng Loh

Institute of Science Tokyo

科研成果: 期刊稿件 › 文章 › 同行评审

4 引用（Scopus）

摘要

Lewis acid-promoted carbonyl-ene reaction of steroidal olefin with a new type of enophile, γ-lactol is shown to exhibit high levels of a-diastereofacial selectivity and 20S, 22R-anti diastereoselectivity to afford 22R, 25-dihydroxy steroid side chains featuring insect moulting steroidal hormones, ecdysones and marine steroid, depresosterol.

源语言	英语
页（从-至）	497-498
页数	2
期刊	Synlett
卷	1993
期	7
DOI	https://doi.org/10.1055/s-1993-22504
出版状态	已出版 - 7月 1993
已对外发布	是

联合国可持续发展目标

此成果有助于实现下列可持续发展目标：

访问文件

10.1055/s-1993-22504

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{5df38b14590a4f3b857db75217359dce,

title = "Lactol-ene reaction: An efficient access to the synthesis of 22R,25-dihydroxy steroid side chains",

abstract = "Lewis acid-promoted carbonyl-ene reaction of steroidal olefin with a new type of enophile, γ-lactol is shown to exhibit high levels of a-diastereofacial selectivity and 20S, 22R-anti diastereoselectivity to afford 22R, 25-dihydroxy steroid side chains featuring insect moulting steroidal hormones, ecdysones and marine steroid, depresosterol.",

author = "Koichi Mikami and Hiroyuki Kishino and Hiroyuki Matsueda and Loh, {Teck Peng}",

year = "1993",

month = jul,

doi = "10.1055/s-1993-22504",

language = "英语",

volume = "1993",

pages = "497--498",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "7",

}

TY - JOUR

T1 - Lactol-ene reaction

T2 - An efficient access to the synthesis of 22R,25-dihydroxy steroid side chains

AU - Mikami, Koichi

AU - Kishino, Hiroyuki

AU - Matsueda, Hiroyuki

AU - Loh, Teck Peng

PY - 1993/7

Y1 - 1993/7

N2 - Lewis acid-promoted carbonyl-ene reaction of steroidal olefin with a new type of enophile, γ-lactol is shown to exhibit high levels of a-diastereofacial selectivity and 20S, 22R-anti diastereoselectivity to afford 22R, 25-dihydroxy steroid side chains featuring insect moulting steroidal hormones, ecdysones and marine steroid, depresosterol.

AB - Lewis acid-promoted carbonyl-ene reaction of steroidal olefin with a new type of enophile, γ-lactol is shown to exhibit high levels of a-diastereofacial selectivity and 20S, 22R-anti diastereoselectivity to afford 22R, 25-dihydroxy steroid side chains featuring insect moulting steroidal hormones, ecdysones and marine steroid, depresosterol.

UR - http://www.scopus.com/inward/record.url?scp=0347966301&partnerID=8YFLogxK

U2 - 10.1055/s-1993-22504

DO - 10.1055/s-1993-22504

M3 - 文章

AN - SCOPUS:0347966301

SN - 0936-5214

VL - 1993

SP - 497

EP - 498

JO - Synlett

JF - Synlett

IS - 7

ER -

Lactol-ene reaction: An efficient access to the synthesis of 22R,25-dihydroxy steroid side chains

摘要

联合国可持续发展目标

访问文件

其它文件与链接

指纹

引用此