TY - JOUR
T1 - New metallocene-bridged cyclodextrin dimer
T2 - A stable derivative of the antitumor drug titanocene dichloride and its potent cytotoxity against human breast cancer (MCF-7) cells
AU - Lu, Zhenda
AU - Lu, Changsheng
AU - Ren, Xiaoming
AU - Meng, Qingjin
PY - 2006/12/15
Y1 - 2006/12/15
N2 - A novel cyclodextrin dimer bridged with titanocene moiety, titanocene di[mono[6-deoxy-6-(2-(thio-1,2-dicyane ethylenylthio)ethyl thio-1,2-dicyane ethylenylthio)]-β-cyclodextrin] (6), has been synthesized and characterized by IR spectroscopy, UV spectroscopy, thermogravimetry, MALDI-TOF MS spectrum, 1H and 13C NMR spectroscopy. Especially, its potent cytotoxity against Human Breast Cancer (MCF-7) has also been studied.
AB - A novel cyclodextrin dimer bridged with titanocene moiety, titanocene di[mono[6-deoxy-6-(2-(thio-1,2-dicyane ethylenylthio)ethyl thio-1,2-dicyane ethylenylthio)]-β-cyclodextrin] (6), has been synthesized and characterized by IR spectroscopy, UV spectroscopy, thermogravimetry, MALDI-TOF MS spectrum, 1H and 13C NMR spectroscopy. Especially, its potent cytotoxity against Human Breast Cancer (MCF-7) has also been studied.
KW - Cytotoxity
KW - Titanocene complex
KW - Titanocene di[mono[6-deoxy-6-(2-(thio-1,2-dicyane ethylenylthio)ethyl thio-1,2-dicyane ethylenylthio)]-β-cyclodextrin]
KW - β-Cyclodextrin dimer
UR - http://www.scopus.com/inward/record.url?scp=33751324359&partnerID=8YFLogxK
U2 - 10.1016/j.jorganchem.2006.09.052
DO - 10.1016/j.jorganchem.2006.09.052
M3 - 文章
AN - SCOPUS:33751324359
SN - 0022-328X
VL - 691
SP - 5895
EP - 5899
JO - Journal of Organometallic Chemistry
JF - Journal of Organometallic Chemistry
IS - 26
ER -
