Palladium-Catalyzed Cross-Electrophile Couplings of Aryl Thianthrenium Salts with Aryl Bromides via C-S Bond Activation

Qian Qian Fu; Yuan Liang; Xiao Xiao Sun; Xue Qiang Chu; Hao Xu; Xiaocong Zhou; Weidong Rao; Zhi Liang Shen

doi:10.1021/acs.orglett.4c03208

Palladium-Catalyzed Cross-Electrophile Couplings of Aryl Thianthrenium Salts with Aryl Bromides via C-S Bond Activation

Qian Qian Fu, Yuan Liang, Xiao Xiao Sun, Xue Qiang Chu, Hao Xu, Xiaocong Zhou, Weidong Rao, Zhi Liang Shen

化学与分子工程学院

科研成果: 期刊稿件 › 文章 › 同行评审

12 引用（Scopus）

摘要

We report here a step-economic and cost-effective cross-electrophile coupling of aryl thianthrenium salts with widely available aryl bromides, which proceeded effectively via C-S bond activation at ambient temperature in THF in the presence of a palladium catalyst, magnesium turnings, and lithium chloride to enable the facile assembly of a wide array of structurally diverse biaryls in modest to good yields with good functional group compatibility. In addition, the gram-scale reaction could also be realized.

源语言	英语
页（从-至）	8577-8582
页数	6
期刊	Organic Letters
卷	26
期	40
DOI	https://doi.org/10.1021/acs.orglett.4c03208
出版状态	已出版 - 11 10月 2024

访问文件

10.1021/acs.orglett.4c03208

其它文件与链接

链接到 Scopus 的出版物

引用此

@article{e0768d6781384745bc2f651bf71ecb13,

title = "Palladium-Catalyzed Cross-Electrophile Couplings of Aryl Thianthrenium Salts with Aryl Bromides via C-S Bond Activation",

abstract = "We report here a step-economic and cost-effective cross-electrophile coupling of aryl thianthrenium salts with widely available aryl bromides, which proceeded effectively via C-S bond activation at ambient temperature in THF in the presence of a palladium catalyst, magnesium turnings, and lithium chloride to enable the facile assembly of a wide array of structurally diverse biaryls in modest to good yields with good functional group compatibility. In addition, the gram-scale reaction could also be realized.",

author = "Fu, {Qian Qian} and Yuan Liang and Sun, {Xiao Xiao} and Chu, {Xue Qiang} and Hao Xu and Xiaocong Zhou and Weidong Rao and Shen, {Zhi Liang}",

note = "Publisher Copyright: {\textcopyright} 2024 American Chemical Society.",

year = "2024",

month = oct,

day = "11",

doi = "10.1021/acs.orglett.4c03208",

language = "英语",

volume = "26",

pages = "8577--8582",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "40",

}

TY - JOUR

T1 - Palladium-Catalyzed Cross-Electrophile Couplings of Aryl Thianthrenium Salts with Aryl Bromides via C-S Bond Activation

AU - Fu, Qian Qian

AU - Liang, Yuan

AU - Sun, Xiao Xiao

AU - Chu, Xue Qiang

AU - Xu, Hao

AU - Zhou, Xiaocong

AU - Rao, Weidong

AU - Shen, Zhi Liang

PY - 2024/10/11

Y1 - 2024/10/11

N2 - We report here a step-economic and cost-effective cross-electrophile coupling of aryl thianthrenium salts with widely available aryl bromides, which proceeded effectively via C-S bond activation at ambient temperature in THF in the presence of a palladium catalyst, magnesium turnings, and lithium chloride to enable the facile assembly of a wide array of structurally diverse biaryls in modest to good yields with good functional group compatibility. In addition, the gram-scale reaction could also be realized.

AB - We report here a step-economic and cost-effective cross-electrophile coupling of aryl thianthrenium salts with widely available aryl bromides, which proceeded effectively via C-S bond activation at ambient temperature in THF in the presence of a palladium catalyst, magnesium turnings, and lithium chloride to enable the facile assembly of a wide array of structurally diverse biaryls in modest to good yields with good functional group compatibility. In addition, the gram-scale reaction could also be realized.

UR - http://www.scopus.com/inward/record.url?scp=85205903679&partnerID=8YFLogxK

U2 - 10.1021/acs.orglett.4c03208

DO - 10.1021/acs.orglett.4c03208

M3 - 文章

C2 - 39348243

AN - SCOPUS:85205903679

SN - 1523-7060

VL - 26

SP - 8577

EP - 8582

JO - Organic Letters

JF - Organic Letters

IS - 40

ER -

Palladium-Catalyzed Cross-Electrophile Couplings of Aryl Thianthrenium Salts with Aryl Bromides via C-S Bond Activation

摘要

访问文件

其它文件与链接

指纹

引用此