Palladium(II)-Catalyzed Stereospecific Alkenyl C-H Bond Alkylation of Allylamines with Alkyl Iodides

Yun Cheng Luo, Chao Yang, Sheng Qi Qiu, Qiu Ju Liang, Yun He Xu, Teck Peng Loh

科研成果: 期刊稿件文章同行评审

34 引用 (Scopus)

摘要

A palladium-catalyzed stereospecific alkylation of allylamines with primary and secondary alkyl iodides is described. Isoquinoline-1-carboxamide (IQA) acts as directing group to generate multisubstituted olefin products in cis configuration in moderate to good yields. Mechanistic studies suggest that alkenyl C-H bond activation is the rate-determining step.

源语言英语
页(从-至)4271-4276
页数6
期刊ACS Catalysis
9
5
DOI
出版状态已出版 - 3 5月 2019
已对外发布

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